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DeCS
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Descriptor English:
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DNA Repair
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Descriptor Spanish:
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Reparación del ADN
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Descriptor Portuguese:
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Reparo do DNA
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Synonyms English:
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Nucleotide Excision Repair
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Tree Number:
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G02.111.087.219
G02.149.115.219
G05.355.195
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Definition English:
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The reconstruction of a continuous two-stranded DNA molecule without mismatch from a molecule which contained damaged regions. The major repair mechanisms are excision repair, in which defective regions in one strand are excised and resynthesized using the complementary base pairing information in the intact strand; photoreactivation repair, in which the lethal and mutagenic effects of ultraviolet light are eliminated; and post-replication repair, in which the primary lesions are not repaired, but the gaps in one daughter duplex are filled in by incorporation of portions of the other (undamaged) daughter duplex. Excision repair and post-replication repair are sometimes referred to as "dark repair" because they do not require light. |
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Indexing Annotation English:
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coord IM with specific DNA (IM)
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See Related English:
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Pyrimidine Dimers
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History Note English:
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74(71)
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Allowable Qualifiers English:
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Record Number:
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4328
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Unique Identifier:
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D004260
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Occurrence in VHL:
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Similar:
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DeCS CID-10 SciELO LILACS LIS
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